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当前位置：首页 > 产品中心抗体产品 > Phospho-Akt(Ser473) Antibody

产品名称	Phospho-Akt(Ser473) Antibody
产品类型	抗体产品
产品货号	201r-0002
产品规格	100μg/100μl
种属
分子量	60kDa
使用注意	Non-conjugated
别名	AKT, AKT1 kinase, C-AKT, EC 2.7.11.1, PKB, PKB-alpha, Protein kinase B, RAC, RAC-PK-alpha, RAC-alpha serine/threonine kinase, kinase Akt1
所需样本体积
反应时间
待测物名称
精密度
研究领域
来源宿主	rabbit
抗体亚型	IgG
储存条件
Swiss序号	P31749
抗体属性	Polyclonal
运用建议	WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-200 IP:1:20-100 Elisa 1:500-5000 Optimal working dilutions must be determined by the end user
纯化	Immunogen affinity purified
抗原	A synthesized peptide derived from human Akt around the phosphorylation site of Sersine 473
保存	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
反应种属	Human, Mouse, Rat
产品图片
产品介绍	an AGC kinase that plays a critical role in controlling the balance between survival and AP0ptosis. Phosphorylated and activated by PDK1 in the PI3 kinase pathway. Mediates survival signals downstream of PI3 kinase and several growth factor receptors by phosphorylating AP0pototic proteins. First found in a mouse transforming retrovirus. Tumorigenic in a mouse lymphoma model and activated (by phospho-Akt staining) and/or overexpressed in a number of cancers including breast, prostate, lung, pancreatic, liver, ovarian and colorectal. Inhibitor: RX-0201. Substrates include tuberin, Bad, Forkhead transcription factors, caspase-9, and glycogen synthase kinase-3.

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