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产品名称	Phospho-CCR5(Ser349) Antibody
产品类型	抗体产品
产品货号	201r-0003
产品规格	100μg/100μl
种属
分子量	40kDa
使用注意	Non-conjugated
别名	Protein name C-C chemokine receptor type 5 ; Synonyms C-C CKR-5; CC-CKR-5; CCR-5; CCR5; HIV-1 fusion coreceptor; CHEMR13; CD195 antigen ; Gene name Name: CCR5 ; Synonyms: CMKBR5
所需样本体积
反应时间
待测物名称
精密度
研究领域
来源宿主	rabbit
抗体亚型	IgG
储存条件
Swiss序号	P51681
抗体属性	Polyclonal
运用建议	WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-200 IP:1:20-100 Elisa 1:500-5000 Optimal working dilutions must be determined by the end user
纯化	Immunogen affinity purified
抗原	A synthesized peptide derived from human CCR5 around the phosphorylation site of Sersine 349
保存	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
反应种属	Human,
产品图片
产品介绍	CCR5 a 7-transmembrane G-linked receptor for a number of inflammatory C-C type chemokines including MIP-1-alpha, MIP-1-beta and RANTES. Transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (along with CD4) for HIV-1 R5 isolates. Interacts with PRAF2. Interacts with HIV-1 surface protein gp120. Efficient ligand binding to CCL3/MIP-1alpha and CCR4/MIP-1beta requires sulfation, O-glycosylation and sialic acid modifications. Glycosylation on S6 is required for efficient binding of CCL4.

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