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抗体产品
> Phospho-CDC25A(Ser75) Antibody
产品名称
Phospho-CDC25A(Ser75) Antibody
产品类型
抗体产品
产品货号
201r-0005
产品规格
100μg/100μl
种属
分子量
59kDa
使用注意
Non-conjugated
别名
CDC25M3, Dual specificity phosphatase Cdc25A, EC 3.1.3.48, M-phase inducer phosphatase 1, MPIP1
所需样本体积
反应时间
待测物名称
精密度
研究领域
来源宿主
rabbit
抗体亚型
IgG
储存条件
Swiss序号
P30304
抗体属性
Polyclonal
运用建议
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-200 IP:1:20-100 Elisa 1:500-5000 Optimal working dilutions must be determined by the end user
纯化
Immunogen affinity purified
抗原
A synthesized peptide derived from human CDC25A around the phosphorylation site of Sersine 75
保存
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
反应种属
Human, Mouse, Rat
产品图片
产品介绍
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
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